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New Case Studies Illustrate the Breadth and Depth of BBK’s Impact

Ever wonder what BBK’s clinical trial support looks like in action? Our newly available case studies show just that!

These resources offer bite-size overviews of some of our thorniest clinical trial recruitment and engagement challenges — revealing the agile and innovative responses that ensure strong results for sponsors.

November 28, 2023

Waldenstrom Macroglobulinemia — Oncology — Phase 2

Our client hired us to provide Concierge travel support to an expansion cohort with Waldenstrom Macroglobulinemia, a ...

Through our TCN Arrive travel service, we created a customized, comprehensive and scalable long-term study visit stay program — all in just two weeks for these Waldenstrom Macroglobulinemia patients.

November 15, 2023

Leber Hereditary Optic Neuropathy — Ophthalmology — Phase 3

BBK Worldwide was hired to make study participation possible, let alone easier, for a group of patients with an acute ...

Leber Hereditary Optic Neuropathy (LHON), TCN Card patient reimbursement, TCN Arrive patient travel

October 17, 2023

Tenosynovial Giant Cell Tumor — Oncology — Phase 3

A rare and difficult-to-treat disease with patients who had suffered from multiple misdiagnoses, failed surgeries, ...

Tenosynovial giant cell tumor (TGCT), also known as pigmented villonodular synovitis (PVNS)

September 25, 2023

Early-Stage Breast Cancer — Oncology — Phase 3

Responding quickly and proactively to a breast cancer diagnosis can often make the difference in the success of a ...

BBK’s bold campaign created discussion opportunities between physicians and patients who were interested, yet hesitant to broach clinical study participation. An empowering message to “Come Out Fighting” coached aggressive pursuit of all treatment options, including this study.  Reigniting a lagging clinical study by getting physicians and patients to talk, BBK ultimately enrolled all 420 patients in only 10 months. Our approach got results with two months to spare — bringing medicine 60 days closer to finding the cure.

August 8, 2023

Early-Stage Parkinson's Disease — Neurology — Phase 2

Partially at-risk media placement, which dictated specific performance indicators for payment, created a partnership ...

The sponsor was looking to investigate a neurology investigational drug for early Parkinson's disease patients — BBK supported recruitment efforts with branded study material development, outreach directing to the program-level study website and prescreener which was further supported by referral management. Media was placed at-risk.

July 10, 2023

Sickle Cell Disease — Hematology — Phase 2

With the study underway, BBK Worldwide was hired to drive enrollment in an increasingly competitive marketplace — and ...

The sponsor was looking to investigate a hematology investigational drug for diverse patients with sickle cell disease (SCD) — BBK supported recruitment efforts by developing study branded materials, developing digital outreach that directed to a study website and prescreener as well as concierge call center referral management.

February 17, 2023

Black and African Americans' Connections to Parkinson's Disease — Neurology — Phase 2

After previous successful recruitment partnerships with BBK Worldwide, the Michael J. Fox Foundation looked to BBK to ...

The sponsor was looking to recruit black or African American Parkinson's disease (PD) patients for an observational study — BBK supported recruitment efforts with branded study material development and digital outreach directing to the program-level study website and prescreener. The messaging was strategized with the assistance of patient interviews done with a patient advisory board.

February 17, 2023

Progressive Multiple Sclerosis — Neurology and Rare Disease — Observational Multicenter Trial

At the completion of the Phase 1 study effort, the sponsor looked to BBK Worldwide to support the recruitment of 80 ...

The sponsor was looking to investigate a neurology investigational drug for patients with progressive multiple sclerosis (MS) — BBK provided recruitment support, initiating study branding and materials, developing digital outreach directing to a study website and prescreener.

October 19, 2022

Enteric Hyperoxaluria — Urology — Phase 1A/B

The client was struggling to enroll a clinical trial evaluating an investigational therapy for enteric hyperoxaluria in ...

The sponsor was looking to investigate a urology investigational drug for enteric hyperoxaluria patients — BBK provided recruitment support, initiating study branding and materials, developing digital outreach directing to a study website and prescreener, further supported by our concierge call center for referral management.

September 13, 2022

Enteric Hyperoxaluria — Urology — Phase 3

The sponsor was seeking to re-energize lagging enrollment for a clinical study for enteric hyperoxaluria.

The sponsor was looking to investigate a urology investigational drug for enteric hyperoxaluria patients — BBK provided rescue recruitment support, initiating study branding and materials, developing digital outreach directing to a study website and prescreener, further supported by our concierge call center for referral management.

August 10, 2022

Amyotrophic Lateral Sclerosis — Rare Neurology and Gene Therapy — Pivotal Study

The VALOR study sought to enroll patients with amyotrophic lateral sclerosis (ALS) who had a mutation in the superoxide ...

The sponsor was looking to investigate a gene therapy investigational drug for rare disease amyotrophic lateral sclerosis (ALS) patients — BBK supported global recruitment and engagement efforts by developing multi-protocol program level study branding and materials, outreach that directed to a study website and prescreener as well as reimbursement and complex travel support.

July 13, 2022

Multiple Myeloma — Oncology — Phase 3

To randomize nearly 900 patients for two global research studies investigating potential new therapies for multiple ...

The sponsor was looking to investigate a oncology investigational drug for multiple myeloma patients — BBK supported global rescue recruitment efforts with branded study material development, consultation around site identification, and a clinician web forum.

June 9, 2022

Early Parkinson's Disease — Neurology — Multiprotocol Program-Level Support

The TemPo studies website and the study recruitment campaign took a sympathetic tone with the understanding that ...

The sponsor was looking to investigate a neurology investigational drug for early Parkinson's disease (PD) patients on a multi-protocol program level — BBK supported recruitment efforts with branded study material development, outreach directing to the program-level study website and prescreener which was further supported by our concierge call center for referral management.

June 9, 2022

South Korean Patients with Esophageal Cancer — Oncology and Gene Therapy — Phase 3

BBK was engaged to support enrollment in South Korea for a study of a PD-1 immune checkpoint inhibitor in patients with ...

The sponsor was looking to investigate a gene therapy oncology investigational drug for esophageal cancer patients — BBK supported South Korean recruitment efforts with by developing health care provider (HCP) or direct-to-physician outreach using database and directing to a study website where they could prescreen patients.

May 17, 2022

Pediatric Boys with Duchenne Muscular Dystrophy — Rare and Gene Therapy — Phase 3B

This clinical study featured a novel investigational approach that appealed to physicians dedicated to advancing ...

The sponsor was looking to investigate a gene therapy investigational drug for boys living with Duchenne Muscular Dystrophy (DMD) — BBK supported global recruitment and engagement efforts by developing study branded materials and outreach directing to a study website and presscreener in addition to providing eBinders and appreciation items for pediatric participants.

April 13, 2022

Overactive Bladder — Urology — Phase 3

BBK Worldwide was hired to support patient recruitment and engagement for a large global study investigating two ...

The sponsor was looking to investigate an urology investigational drug for overactive bladder patients — BBK supported recruitment efforts with study branded materials and outreach directing to a study website and prescreener.

April 13, 2022

Major Depressive Disorder — Mental Health — Pivotal Phase 3 Study

A massive three-year, four-protocol pivotal study requiring over 6,700 global participants demanded the highest level ...

The sponsor was looking to investigate a mental health investigational drug for US patients experiencing Major Depressive Disorder — BBK supported recruitment efforts with study branded outreach like digital media and television directing to a study website and prescreener.

February 5, 2022

Pediatric Spinal Muscular Atrophy — Neurology and Rare Disease — Phase 2

This study evaluated an investigational therapy for spinal muscular atrophy (SMA).

The sponsor was looking to investigate a rare disease investigational drug for global pediatric patients with Spinal Muscular Atrophy (SMA) — BBK developed supporting recruitment and engagement efforts with study branding, materials and outreach directing to a study website and presscreener in addition to reimbursement and complex travel support.

December 13, 2021

Familial Amyloid Polyneuropathy — Neurology and Gene Therapy — Phase 3

BBK Worldwide was engaged by a leading pharmaceutical company for more than six years to provide clinical study travel ...

The sponsor was looking to investigate a rare neurological and inherited disease investigational drug for global familial amyloid polyneuropathy (FAP or TTR) patients — BBK supported engagement efforts with reimbursement, travel and medication delivery support.

October 12, 2021

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